Elderberry Uses, Side Effects & Warnings (2024)

Generic name: elderberry [EL-der-ber-ee]
Brand name: Sambucol
Dosage form: oral liquid (-)
Drug class: Herbal products

Medically reviewed by Drugs.com on Feb 22, 2024. Written by Cerner Multum.

What is elderberry?

Elderberry is a berry from a European or Black elder tree. The berries are used to make medicine.

Elderberry is also known as Arbre de Judas, Baccae, Baises de Sureau, Black-Berried Alder, Black Elder, Boor Tree, Bountry, Elderberries, Ellanwood, Ellhorn, European Alder, Fruit de Sureau, Grand Sureau, Hautbois, Holunderbeeren, Sabugeuiro-negro, Sambequier, Sambu, Sambuc, Sambuci Sambucus, Sambugo, Sauco, Saúco Europeo, Schwarzer Holunder, Seuillet, Seuillon, Sureau, Sureau Noir, Sus, Suseau, or Sussier.

Elderberry should not be confused with American Elder, Elderflower, or Dwarf Elder.

Elderberry has been used in alternative medicine as a possibly effective aid in treating constipation. Elderberry is also possibly effective in reducing the symptoms of influenza (the flu).

Other uses not proven with research have included heart disease, gum disease, high cholesterol, obesity, or the common cold.

It is not certain whether elderberry is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Elderberry should not be used in place of medication prescribed for you by your doctor.

Elderberry is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Elderberry may also be used for purposes not listed in this product guide.

Related/similar drugs

turmeric, Ginkgo Biloba

Elderberry side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although not all side effects are known, elderberry is thought to be possibly safe when taken as directed for a short period of time.

Elderberry is possibly unsafe when uncooked leaves, stems, or fruit are consumed. The elderberry plant contains a chemical that produces cyanide in the leaves or other plant parts and in the unripe green fruit. This can cause nausea, vomiting, and diarrhea, or more serious side effects if consumed in large quantities.

Elderberry may cause serious side effects. Stop using elderberry and call your doctor at once if you have:

  • severe or ongoing vomiting or diarrhea;

  • numbness; or

  • severe weakness, dizziness, or confusion.

Common side effects of elderberry may include:

  • nausea, vomiting;

  • stomach cramps;

  • diarrhea; or

  • runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Elderberry side effects (more detail)

Warnings

Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have an autoimmune disease such as:

  • multiple sclerosis;

  • lupus; or

  • rheumatoid arthritis.

Ask a doctor before using this product if you are pregnant or breastfeeding.

Do not give any herbal/health supplement to a child without medical advice.

How should I take elderberry?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use elderberry, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Do not use different forms of elderberry (pills, liquids, and others) at the same time or you could have an overdose.

Use exactly as directed on the label, or as prescribed by your healthcare provider.

Sambucol is used to relieve cold & flu symptoms such as stuffy nose, runny nose, sneezing, sore throat, cough, fever, and chills. Take at the the first sign of cold or flu symptoms.

If desired, you may mix elderberry liquid with water, fruit juice, yogurt, or a smoothie.

Call your doctor if the condition you are treating with elderberry does not improve, or if you have a fever for more than 3 days or cold symptoms for more than 7 days.

Store your elderberry product as directed away from moisture, heat, and light.

What happens if I miss a dose?

Skip the missed dose and take the next regularly scheduled dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking elderberry?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect elderberry?

Do not take elderberry without medical advice if you are using any of the following medications:

  • medicine to prevent organ transplant rejection;

  • medicine to treat multiple sclerosis;

  • medicine to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders;

  • medicine to treat ulcerative colitis or Crohn's disease; or

  • steroid medicine.

This list is not complete. Other drugs may affect elderberry, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More about elderberry

  • Compare alternatives
  • Reviews (8)
  • Side effects
  • Drug class: herbal products
  • Breastfeeding
  • En español

Patient resources

Other brands

Sambucol

Professional resources

  • Elderberry product monographs

Related treatment guides

  • Herbal Supplementation

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circ*mstances.

Medical Disclaimer

Copyright 1996-2024 Cerner Multum, Inc. Version: 1.01.

Elderberry Uses, Side Effects & Warnings (2024)

FAQs

What are the negative side effects of elderberry? ›

The common side effects of taking raw elderberry plant products, such as fruit, flower, leaves, bark, or root include:
  • Stomach problems.
  • Nausea and vomiting.
  • Diarrhea and constipation.

Who should not take elderberry? ›

Elderberry appears to have few side effects when used properly for short periods of time (up to 5 days). Pregnant and breastfeeding women should not take elderberry. If you have an autoimmune disease, such as rheumatoid arthritis or lupus, ask your doctor before taking elderberry, as it may stimulate the immune system.

Which autoimmune diseases should avoid elderberry? ›

People who have autoimmune conditions such as multiple sclerosis (MS), rheumatoid arthritis, lupus, psoriasis, and inflammatory bowel disease should not use elderberry. Elderberry may boost the immune system, which can worsen autoimmune diseases. Many autoimmune disorders require immunosuppressant drugs.

Is elderberry safe for kidneys? ›

Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks.

Does elderberry affect the heart? ›

Elderberry may have positive effects on some markers of heart and blood vessel health. Studies have shown elderberry juice may reduce the level of fat in the blood and decrease cholesterol. In addition, a diet high in flavonoids like anthocyanins has been found to reduce the risk of heart disease ( 17 , 22 ).

What happens if you take elderberry everyday? ›

Elderberry supplements seem to have few risks when used daily for up to five days. The safety of its long-term use is unknown. Risks. Never eat or drink any product made from raw elderberry fruit, flowers, or leaves.

Can elderberry affect blood pressure? ›

Elderberries may be beneficial for the heart, as they have been associated with positive effects on blood pressure; the anthocyanin content increases the release of nitric oxide—which helps widen the blood vessels and improves blood flow, leading to a decrease in blood pressure.

What medications does elderberry interfere with? ›

Do not take elderberry without medical advice if you are using any of the following medications:
  • medicine to prevent organ transplant rejection;
  • medicine to treat multiple sclerosis;
  • medicine to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders;

Do doctors recommend elderberry? ›

Opinions vary on whether elderberry is helpful, but most doctors believe it's safe to have in small doses. But unripe or uncooked berries or flowers from the plant can cause nausea, vomiting, and diarrhea. Larger amounts can cause even more serious poisoning.

Why can't people with MS take elderberry? ›

Some supplements (e.g., Echinacea, elderberry), when used regularly, may actually worsen MS by overstimulating the immune system. Some supplements may interfere with medications or medical conditions and may not be safe to use.

Why is elderberry not FDA approved? ›

Like elderberry, many other herbal cold remedies are not regulated by the FDA. The few studies conducted on these supplements are not shown to reduce the length of cough and cold symptoms. They also aren't shown to prevent colds or flu.

What does elderberry do to the liver? ›

Long-Term Supplementation of Black Elderberries Promotes Hyperlipidemia, but Reduces Liver Inflammation and Improves HDL Function and Atherosclerotic Plaque Stability in Apolipoprotein E-Knockout Mice.

Is elderberry good for seniors? ›

Elderberry supplements are usually safe for adults, including seniors. However, some medical conditions could make taking elderberry supplements unsafe.

Who shouldn't take elderberry? ›

The toxic materials are destroyed when they are cooked, making them safe to eat. Children and pregnant or breastfeeding women shouldn't eat elderberries at all, since it's not known how the berries might affect them.

Can elderberry have side effects? ›

The elderberry plant contains a chemical that produces cyanide in the leaves or other plant parts and in the unripe green fruit. This can cause nausea, vomiting, and diarrhea, or more serious side effects if consumed in large quantities.

Can I take elderberry with blood pressure medicine? ›

Always talk to your doctor first, especially if you're on any prescription medication, such as blood pressure medications (elderberry products may lower blood pressure, compounding the effect of the drug), on chemotherapy (elderberry may increase the risk of side effects), or if you have been diagnosed with diabetes ( ...

What does elderberry do for your lungs? ›

“While studies have yet to show a direct connection between elderberry and chronic lung conditions, elderberry does contain quercetin, which is a flavonoid and antioxidant that's known to support lung function, especially in those who suffer from asthma and chronic obtrusive pulmonary disease (COPD),” Jones explained.

Can elderberry overstimulate the immune system? ›

For studies examining cytokine storm and other outcomes such as cytokine production, they used three ex vivo studies that suggested elderberry may be safe for treating viral respiratory illness. It does not appear to overstimulate the immune system.

References

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